Ранолазин, но не триметазидин, снижает гликемию, HbA1c и инсулинорезистентность!!!
Ранолазин, но не триметазидин, снижает гликемию, HbA1c и инсулинорезистентность!!! Обзор исследований: 1 Improvement of Vascular Insulin Sensitivity by Ranolazine. Guerra-Ojeda S, Jorda A, Aldasoro C, Vila JM, Valles SL, Arias-Mutis OJ, Aldasoro M. Int J Mol Sci. 2023 Aug 31;24(17):13532. doi: 10.3390/ijms241713532. PMID: 37686345 Free PMC article. 2 Metformin-'BRAINS & AIMS' pharmacological/prescribing principles of commonly prescribed (Top 100) drugs: Education and discussion. Koslover J, Bruce D, Patel S, Webb AJ. Br J Clin Pharmacol. 2023 Mar;89(3):931-938. doi: 10.1111/bcp.15653. Epub 2023 Jan 23. PMID: 36575901 Free article. Review. 3 Effects of ranolazine on various outcomes in patients with stable angina: an updated meta-analysis. Manolis A, Kallistratos M, Poulimenos L, Zamfir T, Thomopoulos C. Hellenic J Cardiol. 2023 May-Jun;71:26-32. doi: 10.1016/j.hjc.2022.12.002. Epub 2022 Dec 5. PMID: 36481415 Free article. 4 The Effects of Ranolazine on Hemoglobin A1c in a Veteran Population. Greiner L, Hurren K, Brenner M. Fed Pract. 2018 May;35(5):44-48. PMID: 30766357 Free PMC article. 5 Effect of ranolazine on glycaemia in adults with and without diabetes: a meta-analysis of randomised controlled trials. Teoh IH, Banerjee M. Open Heart. 2018 Dec 20;5(2):e000706. doi: 10.1136/openhrt-2017-000706. eCollection 2018. PMID: 30613407 Free PMC article. 6 Ranolazine After Incomplete Percutaneous Coronary Revascularization in Patients With Versus Without Diabetes Mellitus: RIVER-PCI Trial. Fanaroff AC, James SK, Weisz G, Prather K, Anstrom KJ, Mark DB, Ben-Yehuda O, Alexander KP, Stone GW, Ohman EM. J Am Coll Cardiol. 2017 May 9;69(18):2304-2313. doi: 10.1016/j.jacc.2017.02.056. PMID: 28473136 Free PMC article. Clinical Trial. 7 Non-haemodynamic anti-anginal agents in the management of patients with stable coronary artery disease and diabetes: A review of the evidence. Ambrosio G, Tamargo J, Grant PJ. Diab Vasc Dis Res. 2016 Mar;13(2):98-112. doi: 10.1177/1479164115609028. PMID: 26873904 Free article. Review. 8 Effect of Ranolazine Monotherapy on Glycemic Control in Subjects With Type 2 Diabetes. Eckel RH, Henry RR, Yue P, Dhalla A, Wong P, Jochelson P, Belardinelli L, Skyler JS. Diabetes Care. 2015 Jul;38(7):1189-96. doi: 10.2337/dc14-2629. Epub 2015 Jun 6. PMID: 26049552 Free PMC article. Clinical Trial. 9 Comparison of ranolazine and trimetazidine on glycemic status in diabetic patients with coronary artery disease - a randomized controlled trial. Sandhiya S, Dkhar SA, Pillai AA, George M, Jayaraman B, Chandrasekaran A. J Clin Diagn Res. 2015 Jan;9(1):OC01-5. doi: 10.7860/JCDR/2015/10594.5448. Epub 2015 Jan 1. PMID: 25738014 Free PMC article. 10 Evaluation of ranolazine in patients with type 2 diabetes mellitus and chronic stable angina: results from the TERISA randomized clinical trial (Type 2 Diabetes Evaluation of Ranolazine in Subjects With Chronic Stable Angina). Kosiborod M, Arnold SV, Spertus JA, McGuire DK, Li Y, Yue P, Ben-Yehuda O, Katz A, Jones PG, Olmsted A, Belardinelli L, Chaitman BR. J Am Coll Cardiol. 2013 May 21;61(20):2038-45. doi: 10.1016/j.jacc.2013.02.011. Epub 2013 Mar 10. PMID: 23500237 Free article. Clinical Trial. 11 Effect of ranolazine on A1C and glucose levels in hyperglycemic patients with non-ST elevation acute coronary syndrome. Chisholm JW, Goldfine AB, Dhalla AK, Braunwald E, Morrow DA, Karwatowska-Prokopczuk E, Belardinelli L. Diabetes Care. 2010 Jun;33(6):1163-8. doi: 10.2337/dc09-2334. Epub 2010 Mar 31. PMID: 20357382 Free PMC article. Clinical Trial. 12 Utility of ranolazine in chronic stable angina patients. Patel PD, Arora RR. Vasc Health Risk Manag. 2008;4(4):819-24. doi: 10.2147/vhrm.s2841. PMID: 19065998 Free PMC article. Review.
Ранолазин, но не триметазидин, снижает гликемию, HbA1c и инсулинорезистентность!!! Обзор исследований: 1 Improvement of Vascular Insulin Sensitivity by Ranolazine. Guerra-Ojeda S, Jorda A, Aldasoro C, Vila JM, Valles SL, Arias-Mutis OJ, Aldasoro M. Int J Mol Sci. 2023 Aug 31;24(17):13532. doi: 10.3390/ijms241713532. PMID: 37686345 Free PMC article. 2 Metformin-'BRAINS & AIMS' pharmacological/prescribing principles of commonly prescribed (Top 100) drugs: Education and discussion. Koslover J, Bruce D, Patel S, Webb AJ. Br J Clin Pharmacol. 2023 Mar;89(3):931-938. doi: 10.1111/bcp.15653. Epub 2023 Jan 23. PMID: 36575901 Free article. Review. 3 Effects of ranolazine on various outcomes in patients with stable angina: an updated meta-analysis. Manolis A, Kallistratos M, Poulimenos L, Zamfir T, Thomopoulos C. Hellenic J Cardiol. 2023 May-Jun;71:26-32. doi: 10.1016/j.hjc.2022.12.002. Epub 2022 Dec 5. PMID: 36481415 Free article. 4 The Effects of Ranolazine on Hemoglobin A1c in a Veteran Population. Greiner L, Hurren K, Brenner M. Fed Pract. 2018 May;35(5):44-48. PMID: 30766357 Free PMC article. 5 Effect of ranolazine on glycaemia in adults with and without diabetes: a meta-analysis of randomised controlled trials. Teoh IH, Banerjee M. Open Heart. 2018 Dec 20;5(2):e000706. doi: 10.1136/openhrt-2017-000706. eCollection 2018. PMID: 30613407 Free PMC article. 6 Ranolazine After Incomplete Percutaneous Coronary Revascularization in Patients With Versus Without Diabetes Mellitus: RIVER-PCI Trial. Fanaroff AC, James SK, Weisz G, Prather K, Anstrom KJ, Mark DB, Ben-Yehuda O, Alexander KP, Stone GW, Ohman EM. J Am Coll Cardiol. 2017 May 9;69(18):2304-2313. doi: 10.1016/j.jacc.2017.02.056. PMID: 28473136 Free PMC article. Clinical Trial. 7 Non-haemodynamic anti-anginal agents in the management of patients with stable coronary artery disease and diabetes: A review of the evidence. Ambrosio G, Tamargo J, Grant PJ. Diab Vasc Dis Res. 2016 Mar;13(2):98-112. doi: 10.1177/1479164115609028. PMID: 26873904 Free article. Review. 8 Effect of Ranolazine Monotherapy on Glycemic Control in Subjects With Type 2 Diabetes. Eckel RH, Henry RR, Yue P, Dhalla A, Wong P, Jochelson P, Belardinelli L, Skyler JS. Diabetes Care. 2015 Jul;38(7):1189-96. doi: 10.2337/dc14-2629. Epub 2015 Jun 6. PMID: 26049552 Free PMC article. Clinical Trial. 9 Comparison of ranolazine and trimetazidine on glycemic status in diabetic patients with coronary artery disease - a randomized controlled trial. Sandhiya S, Dkhar SA, Pillai AA, George M, Jayaraman B, Chandrasekaran A. J Clin Diagn Res. 2015 Jan;9(1):OC01-5. doi: 10.7860/JCDR/2015/10594.5448. Epub 2015 Jan 1. PMID: 25738014 Free PMC article. 10 Evaluation of ranolazine in patients with type 2 diabetes mellitus and chronic stable angina: results from the TERISA randomized clinical trial (Type 2 Diabetes Evaluation of Ranolazine in Subjects With Chronic Stable Angina). Kosiborod M, Arnold SV, Spertus JA, McGuire DK, Li Y, Yue P, Ben-Yehuda O, Katz A, Jones PG, Olmsted A, Belardinelli L, Chaitman BR. J Am Coll Cardiol. 2013 May 21;61(20):2038-45. doi: 10.1016/j.jacc.2013.02.011. Epub 2013 Mar 10. PMID: 23500237 Free article. Clinical Trial. 11 Effect of ranolazine on A1C and glucose levels in hyperglycemic patients with non-ST elevation acute coronary syndrome. Chisholm JW, Goldfine AB, Dhalla AK, Braunwald E, Morrow DA, Karwatowska-Prokopczuk E, Belardinelli L. Diabetes Care. 2010 Jun;33(6):1163-8. doi: 10.2337/dc09-2334. Epub 2010 Mar 31. PMID: 20357382 Free PMC article. Clinical Trial. 12 Utility of ranolazine in chronic stable angina patients. Patel PD, Arora RR. Vasc Health Risk Manag. 2008;4(4):819-24. doi: 10.2147/vhrm.s2841. PMID: 19065998 Free PMC article. Review.
