Ранолазин блокирует α1-адренорецепторы (антиаритмик класса ID)
Biol. Pharm. Bull. 48, 144–150 (2025) Vol. 48, No. 2 https://doi.org/10.1248/bpb.b24-00797 α1-Adrenoceptor Blockade by Class I Antiarrhythmic Drugs in Guinea Pig Thoracic Aorta as Revealed by Mechanical and Fluorescence Displacement Analysis Iyuki Namekata,* Maika Seki, Hiro Igarashi, Kohei Tsukada, Ayaka Kawazoe, Kuniaki Shirai, Marina Miyahara, Shogo Hamaguchi, and Hikaru Tanaka Department of Pharmacology, Faculty of Pharmaceutical Sciences, Toho University, 2–2–1 Miyama, Funabashi, Chiba 274–8510, Japan. *Correspondence: iyuki@phar.toho-u.ac.jp © 2025 Author(s) This is an open access article distributed under the terms of Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/). Published by The Pharmaceutical Society of Japan Received: November 24, 2024; accepted: December 23, 2024 https://www.jstage.jst.go.jp/article/bpb/48/2/48_b24-00797/_pdf/-char/en
Biol. Pharm. Bull. 48, 144–150 (2025) Vol. 48, No. 2 https://doi.org/10.1248/bpb.b24-00797 α1-Adrenoceptor Blockade by Class I Antiarrhythmic Drugs in Guinea Pig Thoracic Aorta as Revealed by Mechanical and Fluorescence Displacement Analysis Iyuki Namekata,* Maika Seki, Hiro Igarashi, Kohei Tsukada, Ayaka Kawazoe, Kuniaki Shirai, Marina Miyahara, Shogo Hamaguchi, and Hikaru Tanaka Department of Pharmacology, Faculty of Pharmaceutical Sciences, Toho University, 2–2–1 Miyama, Funabashi, Chiba 274–8510, Japan. *Correspondence: iyuki@phar.toho-u.ac.jp © 2025 Author(s) This is an open access article distributed under the terms of Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/). Published by The Pharmaceutical Society of Japan Received: November 24, 2024; accepted: December 23, 2024 https://www.jstage.jst.go.jp/article/bpb/48/2/48_b24-00797/_pdf/-char/en